The Town of Ione continued to grow and prosper after its gold rush founding. The first school was built in 1853. The historic Methodist Church was organized in 1853 and the structure was completed in 1862.

brick building was built by Daniel Stewart in 1855 for his general merchandise store and is still owned by the same family.
At the centennial of 1876, Ione had a population of about 600 which included about 100 Chinese who lived in Ione's Chinatown. The town included one public school, 4 churches, 4 general stores, one meat market, one laundry, one brewery, a restaurant, a millinery shop, an art gallery, six saloons, a drug store and barber shop, and many other business establishments. The centennial also celebrated the completion of the railroad to the town of Ione. The centennial celebration was the beginning of what is now known as the Ione Homecoming. This annual celebration has been held during the month of May almost every year since that first Centennial celebration in 1876 and is now held on the second weekend in May annually.
The City of Ione was incorporated as a General Law City in 1953 and is now the largest city in Amador County.
